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The complexes consisting of viral peptides and HLA molecules are then transported to the cell surface, where they are presented. Please find more information in our privacy statement. Short-wave infrared can also penetrate deeper into tissue, although calculating exactly how far is a complicated process, the researchers say, because it depends on the size of the structure being viewed and the field of view of the microscope. For these procedures, as well as others now in clinical trials, such as imaging tumors, researchers use a portion of the light spectrum known as the near-infrared NIR — to nanometers, just beyond what the human eye can detect. When T cells detect such a complex on the surface of a cell, they recognize that the cell is infected and initiate its destruction.

  • Press Release – Helmholtz Zentrum München
  • Universität Düsseldorf Studying

  • Press Release – Helmholtz Zentrum München

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    Previous studies of ICG had focused on its emission around nanometers, where it fluoresces the brightest, so no one had observed that the dye also produced a strong signal at longer wavelengths. There you may also change your settings later. We use different types of cookies.

    Light with shorter wavelengths tends to scatter off of imperfections in objects that it strikes, but as wavelengths become longer, scattering is greatly reduced.

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    Cross-sectional analysis of CD8 T cell immunity to human herpesvirus 6B.

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    Most people acquire human herpesvirus 6, or HHV-6 for short, in early childhood. A dye that fluoresces at this wavelength is administered to the body or tissue and then imaged using a specialized camera.

    Normally, this depth can be reached only with two-photon microscopy, a much more complicated and expensive type of imaging. Statistical cookies Matomo Permit cookies that help us to analyse the page views and user behavior on our websites.

    The researchers also found that ICG is bright enough that it can produce images quickly, which is important for capturing motion.

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    Universität Düsseldorf Studying

    The research team is now further investigating why ICG works so well for shortwave-infrared imaging, and is trying to identify the optimal wavelength for its use, which they hope will help them determine the best applications for this kind of imaging. The Research Unit Gene Vectors studies EBV's molecular functions to understand how the virus contributes to different types of disease. The long-term goal is to develop T-cell-based strategies to prevent and cure diseases caused by those viruses.

    Most people acquire human herpesvirus 6, or HHV-6 for short, in early childhood. They have shown that an FDA-approved, commercially available dye now used for near-infrared imaging also works very well for short-wave infrared imaging.

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    Although HHV-6 does not affect the health of most people, it is suspected to contribute to autoimmune diseases and chronic fatigue syndrome.

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    Fluorescence imaging is widely used for visualizing biological tissues such as the back of the eye, where signs of macular degeneration can be detected. We use cookies to improve your experience on our Website. There you may also change your settings later.

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      Malmaran

      To achieve this, it investigates the interaction of genetics, environmental factors and lifestyle. There you may also change your settings later.

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